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RHEUMATOID ARTHRITIS • Rheumatoid arthritis (RA) is a chronic and usually progressive inflammatory disorder of unknown etiology characterized by polyarticular symmetric joint involvement and systemic manifestations. • RA results from a dysregulation of the humoral and cell-mediated components of the immune system. Most patients produce antibodies called rheumatoid factors; these seropositive patients tend to have a more aggressive course than patients who are seronegative . • Immunoglobulins (Igs) can activate the complement system, which amplifies the immune response by enhancing chemotaxis, phagocytosis, and release of lymphokines by mononuclear cells that are then presented to T lymphocytes. The processed antigen is recognized by the major histocompatibility complex proteins on the lymphocyte surface, resulting in activation of ...

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HOW MUCH CARDIO YOU REALLY NEED?

ABOUT CARDIO It seems like I see the same people on the cardio machines every time I go to the gym. They run, climb, or cycle for over an hour – and yes they do work up a sweat, but they’re also unknowingly burning their precious muscle away. Often, they’ll wonder why they don’t look leaner, or why they’ve hit a plateau with their routines. Cardio provides so many incredible benefits. It makes our heart stronger, increases endurance, burns calories/fat, can make you faster, and most of the time, it can be a lot of fun. But, after a certain point, you can actually start to see diminishing returns from cardio if you’re doing too much. So, how do we find the sweet spot? According to the recommendations from The American College of Sports Medicine and the U.S. Department of Health and Human Services, we should be aiming for at least 150 minutes of moderate-intensity cardiorespiratory exercise, 75 minutes of vigorous-intensity, or a combin...

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ESSENTIAL INSURANCE TIPS

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